About — Manish Kumar · OmniBioAI
Manish Kumar
Senior Computational Scientist · AI Platform Engineer

18+ years solving the hardest problems in bioinformatics — from raw sequencing reads to clinical-grade insights. I built OmniBioAI because fragmented, hard-to-reproduce tools were slowing down real science.

KUMC · Kansas City, USA
18+ years experience
5 countries · 3 publications
Solo builder · Open to collaboration
18+Years experience
5Countries
36MPubMed abstracts
2.1MLines of code
28Microservices
600+Pipelines

// The story

Built solo, out of necessity

I built OmniBioAI alone. No team, no funding rounds — just 18 years of accumulated frustration with the state of bioinformatics tooling and a DGX Spark to make it real.

After working across genomics, proteomics, and drug discovery pipelines at hospitals, universities, and genomics labs spanning India, Malaysia, Qatar, Saudi Arabia, and the United States, I kept hitting the same walls: tools that broke between clusters, pipelines that couldn't be reproduced, AI that couldn't reason about biology.

"Every lab was rebuilding the same infrastructure in isolation. I decided to build the platform I always wished existed — and ship it as a single desktop install."

What started as a personal toolkit is now a production system: 2.1M lines of code, 28 microservices, 36M PubMed abstracts indexed, 600+ workflow bundles, and 1 PetaFLOP of AI compute — built by one person over three years.

The mission

Modern bioinformatics is fragmented. A graduate student's analysis breaks when they move to a new HPC. A clinical team revalidates pipelines every time a tool version changes. Literature search is disconnected from computation. AI assistants hallucinate biology.

OmniBioAI is my answer: a reproducible, AI-native operating system for biomedical research that runs identically on a laptop, a Slurm cluster, or AWS — with a 9-stage RAG pipeline over 36M PubMed abstracts, full LIMS integration, and provenance from raw FASTQ to final biological insight.

Currently a Bioinformatics Programmer and Research Associate at the University of Kansas Medical Center (KUMC), I build OmniBioAI in the margins — nights, weekends, and every spare hour. It is a solo project in the truest sense.


// Experience

Career timeline

Bioinformatics Programmer / Research Associate
Oct 2024 – Present
University of Kansas Medical Center
Kansas City, KS, USA
Bioinformatics Software Engineer II
Mar 2021 – Aug 2024
Children's Mercy Kansas City
Kansas City, MO, USA
Bioinformatics IT Specialist II
Feb 2019 – Mar 2021
University of Tennessee
Knoxville, TN, USA
Bioinformatician (Consultant)
Apr 2018 – Oct 2018
King Faisal Specialist Hospital International (KFSHI)
Riyadh, Saudi Arabia
Senior Research Specialist Bioinformatician Programmer
Sep 2014 – Sep 2017
Weill Cornell Medical College in Qatar
Doha, Qatar
Senior Bioinformatics Software Developer
Aug 2008 – Aug 2014
Synamatix Sdn Bhd
Kuala Lumpur, Malaysia
Bioinformatics Programmer
Jul 2007 – Aug 2008
Systems Biology India Pvt. Ltd.
Pune, Maharashtra, India
Project Trainee
Feb 2006 – Jul 2006
Centre for DNA Fingerprinting and Diagnostics (CDFD)
Hyderabad, Telangana, India

// Technical expertise

Skills & stack

Omics & Genomics
scRNA-seq WGS/WES ATAC-seq ChIP-seq Proteomics Spatial TX Methylation CRISPR
AI & ML
LangGraph PyTorch HuggingFace Ollama GNNs RAG CUDA
Workflow engines
Nextflow WDL Snakemake CWL Slurm
Bioinformatics tools
GATK Seurat DESeq2 GSEA SnpEff STAR BWA
Platform & infrastructure
Docker Kubernetes AWS Azure GCP FastAPI Django Celery Redis
Languages
Python R Bash SQL JavaScript

// Publications

Peer-reviewed research

2025
Genetic mutations in lymphocytic variant of hypereosinophilic syndrome: study of five siblings
Frontiers in Medicine · December 2025
↗ View paper
2018
Whole Exome Sequencing identifies common and rare variant Metabolic QTLs in a Middle Eastern Population
Nature Communications · January 2018
↗ View paper
2015
MetaRNA-Seq: An Interactive Tool to Browse and Annotate Metadata from RNA-Seq Studies
BioMed Research International · August 2015
↗ View paper

Interested in collaborating?

Whether you're a researcher, institution, or biotech — I'd love to hear about your multi-omics challenges.