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Although most dynamic languages like JavaScript already include support for HTTP and JSON where in most cases it's easier to just use the libraries already provided. Here are a couple of examples from Backbones Todos and Redis StackOverflow that uses jQuery to talk to back-end ServiceStack JSON services:
JSV is marginally faster than safe JSON in modern browsers (marginally slower than Eval) but because of the poor JS and String Performance in IE7/8 it performs over 20x slower than IE's native eval().