OpenScience

Copyright 2026 Synthetic Sciences

This product includes software developed at Synthetic Sciences.

Licensed under the Apache License, Version 2.0.

It bundles or accesses the following third-party software and services.

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OpenCode

https://github.com/anomalyco/opencode · https://opencode.ai

OpenScience is inspired by OpenCode and its work toward excellent open-source

agents. OpenScience applies that inspiration to making strong, open-source

scientific agents available to everyone.

MIT License

Copyright (c) 2025 opencode

Permission is hereby granted, free of charge, to any person obtaining a copy

of this software and associated documentation files (the "Software"), to deal

in the Software without restriction, including without limitation the rights

to use, copy, modify, merge, publish, distribute, sublicense, and/or sell

copies of the Software, and to permit persons to whom the Software is

furnished to do so, subject to the following conditions:

The above copyright notice and this permission notice shall be included in all

copies or substantial portions of the Software.

THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR

IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,

FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE

AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER

LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,

OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE

SOFTWARE.

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Scientific Agent Skills (bundled scientific skills under backend/cli/skills/)

https://github.com/K-Dense-AI/scientific-agent-skills

Copyright (c) 2025 K-Dense Inc.

Licensed under the MIT License. See https://github.com/K-Dense-AI/scientific-agent-skills/blob/main/LICENSE.md.

166 of the bundled skills (biology, chemistry, databases, coding, data

engineering, physics, quantum, research, visualization and writing) are

derived from this collection, including skills taken from its earlier

scientific-skills/, scientific-databases/ and scientific-packages/ layout.

backend/cli/skills/ATTRIBUTION.md lists every one with its upstream path, and

each skill's frontmatter records the same under metadata.upstream. The

collection is described in Kassis, Agarwal, He, Patel and Brueckner,

"Scientific Agent Skills: A Library of Procedural Knowledge for Research

Agents", arXiv:2609.00065 (2026); cite it when these skills contribute to

published work.

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Claude Scientific Writer (bundled skills under backend/cli/skills/)

https://github.com/K-Dense-AI/claude-scientific-writer

Copyright (c) 2025-2026 K-Dense Inc.

Licensed under the MIT License.

The posters, slides, infographics and research-grants skills, and the style

references, review checklists and schematic scripts inside the core

paper-writing, ml-paper-writing, peer-review, hypotheses, literature-review,

schematics, citations, sources and brainstorming skills are derived from this

collection. See backend/cli/skills/ATTRIBUTION.md.

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AI Research Skills (bundled ML skills under backend/cli/skills/)

https://github.com/Orchestra-Research/AI-Research-SKILLs

Copyright (c) 2025 Claude AI Research Skills Contributors (Orchestra Research)

Licensed under the MIT License.

79 of the bundled skills (ml-training, ml-inference, llm-tools, cloud-compute

and related coding skills) are derived from this collection. See

backend/cli/skills/ATTRIBUTION.md.

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Hugging Face skills (bundled hugging-face-* skills under backend/cli/skills/)

https://github.com/huggingface/skills

Copyright Hugging Face.

Licensed under the Apache License, Version 2.0.

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Anthropic document skills (backend/cli/skills/document-parsing/{docx,pdf,pptx,xlsx})

https://github.com/anthropics/skills

© 2025 Anthropic, PBC. All rights reserved.

Used under Anthropic's terms; each skill directory keeps Anthropic's LICENSE.txt.

Vendored through the K-Dense collections, which track the Anthropic originals.

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NVIDIA BioNeMo Agent Toolkit (backend/cli/skills/biology/protein-binder-design)

https://github.com/NVIDIA-BioNeMo/bionemo-agent-toolkit

Copyright NVIDIA Corporation.

Skills and documentation licensed under CC-BY-4.0; code under the Apache

License, Version 2.0; the models the workflow calls carry their own terms.

Pinned source revision: 0e67a612e4045f007e38fa77adc8f3ebfc5616b6.

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pacsomatic (backend/cli/skills/biology/pacsomatic)

Copyright (c) 2026 Beifang Niu

Licensed under the MIT License. See the skill's LICENSE.

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markitdown (bundled skill: backend/cli/skills/data-engineering/markitdown)

https://github.com/microsoft/markitdown

Copyright (c) Microsoft Corporation.

Licensed under the MIT License. See the skill's LICENSE.txt.

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conducting-scientific-research and scientific-problem-selection bundled skills

https://github.com/Shoko-official/Claude-Science-System-Prompts

Copyright 2026 Shoko-official contributors.

Licensed under the Apache License, Version 2.0.

Pinned source revision: a55a1709d36534d42462b51f61f9859bf4ab23b6.

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Iconoir icons (bundled in frontend/ui/src/components/iconoir-registry.ts)

https://github.com/iconoir-icons/iconoir

MIT License

Copyright (c) 2021 Luca Burgio

Permission is hereby granted, free of charge, to any person obtaining a copy

of this software and associated documentation files (the "Software"), to deal

in the Software without restriction, including without limitation the rights

to use, copy, modify, merge, publish, distribute, sublicense, and/or sell

copies of the Software, and to permit persons to whom the Software is

furnished to do so, subject to the following conditions:

The above copyright notice and this permission notice shall be included in all

copies or substantial portions of the Software.

THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR

IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,

FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE

AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER

LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,

OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE

SOFTWARE.

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Third-party scientific data sources

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The scientific database connectors under backend/cli/src/science/connectors/

access third-party public web APIs (including, among others, UniProt, RCSB PDB,

PDBe, AlphaFold DB, InterPro, Ensembl, NCBI E-utilities, ClinVar, gnomAD, UCSC,

ChEMBL, PubChem, ChEBI, Reactome, KEGG, STRING, IntAct, WikiPathways,

Open Targets, GEO, ArrayExpress, GTEx, the Human Protein Atlas, Europe PMC,

Crossref, OpenAlex, Semantic Scholar, arXiv, and bioRxiv). OpenScience does not

redistribute the data served by these APIs. Each source is governed by its own

terms of use and licensing; users are responsible for complying with the terms

of any data source they query.

Client-side rendering libraries (Mol*, igv.js, RDKit.js, KaTeX, pdf.js, 3Dmol.js)

are dependencies declared in package.json and retain their own licenses. The CLI

binary bundles unpdf (MIT) and the build of pdf.js (Apache-2.0) it ships, for PDF

text extraction; both retain their own licenses.

Fonts

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Computer Modern Unicode (CMU Concrete; frontend/landing/public/fonts,

frontend/workspace/public/fonts/cmc, frontend/docs/public/fonts/cmc) and Inter

(frontend/landing/public/fonts) are bundled under the SIL Open Font License 1.1;

the OFL text sits next to each font.