isolated-vm supports loading native compiled modules. In this directory is an example module to get you started. Your code must be isolate-aware, context-aware, and thread-safe. Using nan [Native Abstractions for Node] as demonstrated here will get you most of the way there since all those functions are isolate and context-aware. Sometimes existing native modules can be modified to support isolated-vm with very few changes at all.

You should not use libuv in isolated-vm, except in the default isolate. Also, asynchronous callbacks are not supported except for the default isolate.